Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338898 | 0.92 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11348581 | 0.81 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11342135 | 0.78 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11341250 | 0.78 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11346404 | 0.77 | IGF1R (0.82) | IGF1R | |
| SCHEMBL11343486 | 0.76 | IGF1R (0.83) | IGF1RNTRK1 | |
| SCHEMBL11339535 | 0.76 | IGF1R (1.00) | IGF1R | |
| SCHEMBL11347979 | 0.75 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11344767 | 0.74 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11341602 | 0.74 | IGF1R (1.00) | IGF1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841760-B1 | PYRIMIDINE DERIVATIVES AS KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2011-08-10 | — | — | EP | disclosed |