Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 6/20 | 0.45 |
| ▸ | CHUK | O15111 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022885 | 0.82 | TLR7 (0.46) | — | |
| SCHEMBL2815566 | 0.80 | HTR2C (0.51) | HTR2CTOP2AIKBKBCHUKKDM4E | |
| SCHEMBL16520172 | 0.80 | TLR7 (0.34) | KDM4ESMN1; SMN2BRD4MEN1KMT2A | |
| SCHEMBL2815787 | 0.79 | HTR2C (0.50) | HTR2CTOP2AIKBKBCHUKKDM4E | |
| SCHEMBL2819718 | 0.75 | IKBKB (0.69) | HTR2CTOP2AIKBKBCHUKKDM4E | |
| SCHEMBL2816677 | 0.73 | HTR2C (0.51) | HTR2CTOP2AIKBKBCHUKKDM4E | |
| SCHEMBL14884413 | 0.72 | TLR7 (0.48) | MEN1KMT2A | |
| SCHEMBL17895220 | 0.72 | IKBKB (0.49) | HTR2CTOP2AIKBKBCHUKKDM4E | |
| SCHEMBL2815167 | 0.72 | HTR2C (0.47) | HTR2CTOP2AIKBKBCHUKKDM4E | |
| SCHEMBL2815052 | 0.72 | HTR2C (0.47) | HTR2CTOP2AIKBKBCHUKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357184-A1 | Imidazoquinoxaline compounds as immunomodulators | Novartis AG (CH) | 2011-08-17 | — | — | EP | disclosed |