Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 9/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088450 | 0.88 | MAOB (0.39) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL13350123 | 0.87 | MAOB (0.39) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL10088570 | 0.86 | MAOB (0.38) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL2330461 | 0.86 | MAOB (0.39) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL10088575 | 0.85 | MAOB (0.37) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL10088572 | 0.84 | MAOB (0.36) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL2323503 | 0.84 | S1PR1 (0.49) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL2325179 | 0.83 | MAOB (0.37) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL10088400 | 0.83 | MAOB (0.39) | ALOX5MAOBMAOAS1PR4S1PR1 | |
| SCHEMBL10088637 | 0.80 | MAOB (0.39) | ALOX5MAOBMAOAFFAR1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354134-A1 | 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF | Astellas Pharma Inc. (JP) | 2011-08-10 | — | — | EP | disclosed |