Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.65 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | ACVR2A | P27037 | 3/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16116782 | 0.89 | LOX (0.55) | DYRK1ALOXLOXL2LRRK2S1PR1 | |
| SCHEMBL30626327 | 0.89 | LOX (0.55) | DYRK1ALOXLOXL2LRRK2S1PR1 | |
| SCHEMBL18481804 | 0.84 | LOX (0.47) | DYRK1ALOXLOXL2LRRK2S1PR1 | |
| SCHEMBL13036116 | 0.84 | DYRK1A (0.55) | DYRK1ALOXLOXL2LRRK2S1PR1 | |
| SCHEMBL1896511 | 0.82 | DYRK1A (0.65) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| SCHEMBL30308690 | 0.82 | DYRK1A (0.65) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| SCHEMBL94462 | 0.82 | DYRK1A (0.49) | DYRK1ALOXLOXL2LRRK2S1PR1 | |
| SCHEMBL14970135 | 0.82 | DYRK1A (0.62) | DYRK1ALOXL2CYP19A1 | |
| SCHEMBL30042310 | 0.82 | DYRK1A (0.49) | DYRK1ALOXLOXL2LRRK2S1PR1 | |
| SCHEMBL29141734 | 0.82 | DYRK1A (0.53) | DYRK1ALOXLOXL2LRRK2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773775-B1 | SIX-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-08-17 | — | — | EP | disclosed |