Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 11/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913785 | 0.89 | SCNN1A (0.53) | SCNN1A | |
| Hydrochloric Acid SCHEMBL2329255 | 0.89 | SCNN1A (0.52) | SCNN1A | |
| SCHEMBL12442498 | 0.86 | SCNN1A (0.41) | SCNN1A | |
| SCHEMBL12443046 | 0.85 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL12442490 | 0.85 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL12443055 | 0.82 | SCNN1A (0.50) | SCNN1A | |
| SCHEMBL12433383 | 0.82 | SCNN1A (0.53) | SCNN1A | |
| SCHEMBL13979964 | 0.82 | SCNN1A (0.40) | SCNN1A | |
| SCHEMBL13980001 | 0.81 | SCNN1A (0.39) | SCNN1A | |
| SCHEMBL12443281 | 0.81 | SCNN1A (0.47) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485360-B1 | SODIUM CHANNEL BLOCKERS | PARION SCIENCES INC (US) | 2011-08-17 | — | — | EP | disclosed |