SCHEMBL12445443

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27375087	1.00	MEN1 (0.50)	MEN1KMT2AMTNR1AMTNR1BKDM4E
	SCHEMBL17921779	0.98	MEN1 (0.47)	MEN1KMT2AMTNR1AMTNR1BKDM4E
	SCHEMBL18866794	0.87	MEN1 (0.41)	MEN1KMT2AMTNR1AMTNR1BKDM4E
	SCHEMBL22790989	0.86	MEN1 (0.50)	MEN1KMT2AMTNR1AMTNR1BKDM4E
	SCHEMBL22861923	0.86	MEN1 (0.50)	MEN1KMT2AMTNR1AMTNR1BKDM4E
	SCHEMBL23945213	0.86	MEN1 (0.50)	MEN1KMT2AMTNR1AMTNR1BKDM4E
	SCHEMBL25128825	0.86	KMT2A (0.59)	MEN1KMT2AMTNR1AKDM4EMAPK1
	SCHEMBL25129535	0.86	KMT2A (0.59)	MEN1KMT2AMTNR1AKDM4EMAPK1
	SCHEMBL23386933	0.86	MEN1 (0.50)	MEN1KMT2AALDH1A1HPGDTSHR
	SCHEMBL27371560	0.86	KMT2A (0.59)	MEN1KMT2AMTNR1AKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.