Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445527 | 0.84 | BACE1 (0.58) | BACE1CTSD | |
| SCHEMBL12446166 | 0.78 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL287115 | 0.78 | BACE1 (0.84) | BACE1 | |
| SCHEMBL7941420 | 0.78 | BACE1 (0.84) | BACE1 | |
| SCHEMBL286822 | 0.78 | BACE1 (0.69) | BACE1 | |
| SCHEMBL286821 | 0.78 | BACE1 (0.69) | BACE1 | |
| SCHEMBL286820 | 0.78 | BACE1 (0.69) | BACE1 | |
| SCHEMBL287267 | 0.77 | BACE1 (0.71) | BACE1 | |
| SCHEMBL287268 | 0.77 | BACE1 (0.71) | BACE1 | |
| SCHEMBL287269 | 0.77 | BACE1 (0.71) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360155-A1 | 2-AMINOPYRIDIN-4-ONE AND 2-AMINOPYRIDINE DERIVATIVE BOTH HAVING BACE1-INHIBITING ACTIVITY | Shionogi & Co., Ltd. (JP) | 2011-08-24 | — | — | EP | disclosed |