Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 4/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244337 | 0.94 | NR1I2 (0.58) | NR1I2PIM1PIM3PIM2FGFR3 | |
| SCHEMBL1244274 | 0.90 | NR1I2 (0.53) | NR1I2PIM1PIM3PIM2 | |
| SCHEMBL1244742 | 0.76 | NR1I2 (0.58) | NR1I2FGFR3 | |
| SCHEMBL1242149 | 0.74 | NR1I2 (1.00) | NR1I2 | |
| SCHEMBL1242063 | 0.73 | NR1I2 (0.57) | NR1I2 | |
| SCHEMBL1243683 | 0.73 | NR1I2 (0.59) | NR1I2 | |
| SCHEMBL1243508 | 0.72 | NR1I2 (0.53) | NR1I2 | |
| SCHEMBL1244588 | 0.72 | NR1I2 (0.66) | NR1I2FGFR3 | |
| SCHEMBL12445707 | 0.71 | NR1I2 (0.80) | NR1I2 | |
| SCHEMBL1241942 | 0.71 | NR1I2 (0.68) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183959-A1 | P38 KINASE INHIBITING AGENTS | CHEN MENG-HSIN | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183959-A1 | P38 KINASE INHIBITING AGENTS | MAPK1, MAPK8, MAPK7 | NR1I2 589/4885PIM1 2541/4885PIM3 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.