⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12447483 | 0.84 | — | — | |
| SCHEMBL12521621 | 0.83 | — | — | |
| SCHEMBL12521624 | 0.74 | — | — | |
| SCHEMBL17278237 | 0.73 | — | — | |
| SCHEMBL331406 | 0.69 | — | — | |
| SCHEMBL2608976 | 0.67 | — | — | |
| SCHEMBL1456499 | 0.67 | — | — | |
| SCHEMBL3862417 | 0.65 | — | — | |
| SCHEMBL1456497 | 0.65 | — | — | |
| SCHEMBL9804918 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738922-B2 | Universal methylation profiling methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-08-22 | — | — | US | disclosed |
| US-9738922-B2 | Universal methylation profiling methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-08-22 | — | — | US | disclosed |
| US-20150148240-A1 | UNIVERSAL METHYLATION PROFILING METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-05-28 | — | — | US | disclosed |
| US-20110177508-A1 | UNIVERSAL METHYLATION PROFILING METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2011-07-21 | — | — | US | disclosed |
| US-20110177508-A1 | UNIVERSAL METHYLATION PROFILING METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2011-07-21 | — | — | US | disclosed |