⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12447484 | 0.78 | — | — | |
| SCHEMBL14018483 | 0.74 | — | — | |
| SCHEMBL14535268 | 0.65 | — | — | |
| SCHEMBL9977638 | 0.65 | — | — | |
| SCHEMBL22053717 | 0.63 | — | — | |
| SCHEMBL19346348 | 0.63 | — | — | |
| SCHEMBL19261459 | 0.63 | — | — | |
| SCHEMBL12166887 | 0.63 | — | — | |
| SCHEMBL26528659 | 0.63 | — | — | |
| SCHEMBL15037526 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120051-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |
| EP-3208272-A1 | HETEROCYCLIC MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9738922-B2 | Universal methylation profiling methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-08-22 | — | — | US | disclosed |
| US-20150148240-A1 | UNIVERSAL METHYLATION PROFILING METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-05-28 | — | — | US | disclosed |
| US-20110177508-A1 | UNIVERSAL METHYLATION PROFILING METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2011-07-21 | — | — | US | disclosed |