SCHEMBL12448043

SCHEMBL12448043

C=C(C)c1cccc(C(=C)Br)c1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FURIN P09958 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 2/20 0.35
HTT P42858 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167439 0.88 FURIN (0.43) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL6252421 0.85 FURIN (0.41) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL17421702 0.85 FURIN (0.41) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL30834584 0.85 FURIN (0.41) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL1536276 0.81 FURIN (0.39) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL992992 0.77 C1S (0.52) L3MBTL1TSHRALDH1A1
SCHEMBL12449051 0.77 FURIN (0.36) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL12448044 0.77 FURIN (0.36) FURINL3MBTL1TDP1TSHRHTT
SCHEMBL4105605 0.77 TDP1 (0.56) L3MBTL1TDP1HTTMAPTLMNA
SCHEMBL11864083 0.77 PARP1 (0.52) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2314635-B1 METHOD FOR MEASURING A PERFLUORO COMPOUND WITH A FILLER WAKO PURE CHEM IND LTD (JP) 2017-12-20 EP disclosed
EP-2359931-B1 POLYMER FILLER FOR PREPROCESSING COLUMN WAKO PURE CHEM IND LTD (JP) 2016-04-20 EP disclosed
US-9110087-B2 Polymer for filler for preprocessing column WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-18 US disclosed
US-9110087-B2 Polymer for filler for preprocessing column WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-18 US disclosed
US-20130309775-A1 POLYMER FOR FILLER FOR PREPROCESSING COLUMN NIPPON FILCON CO., LTD. (JP) 2013-11-21 US disclosed
EP-2359931-A2 Polymer filler for preprocessing column Wako Pure Chemical Industries, Ltd. (JP) 2011-08-24 EP disclosed
US-20110138935-A1 POLYMER FOR FILLER FOR PREPROCESSING COLUMN WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-06-16 US disclosed
US-20110138935-A1 POLYMER FOR FILLER FOR PREPROCESSING COLUMN WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-06-16 US disclosed
EP-2314635-A1 POLYMER FOR FILLER FOR PREPROCESSING COLUMN Wako Pure Chemical Industries, Ltd. (JP) 2011-04-27 EP disclosed