Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.64 |
| ▸ | MAOA | P21397 | 8/20 | 0.64 |
| ▸ | ACHE | P22303 | 6/20 | 0.64 |
| ▸ | BCHE | P06276 | 2/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17887837 | 0.84 | MAOB (0.66) | MAOBMAOAACHEBCHEADRA2B | |
| SCHEMBL12450625 | 0.82 | MAOB (0.64) | MAOBMAOAACHEBCHEADRA2B | |
| SCHEMBL5003611 | 0.82 | MAOB (0.79) | MAOBMAOAACHEBCHEADRA2B | |
| SCHEMBL333100 | 0.82 | MAOB (0.64) | MAOBMAOAACHEBCHEADRA2B | |
| Hydrochloric Acid SCHEMBL7337173 | 0.81 | MAOB (0.62) | MAOBMAOAACHEBCHEADRA2B | |
| Rasagiline SCHEMBL333333 | 0.78 | MAOB (1.00) | MAOBMAOAACHEBCHEADRA2B | |
| Rasagiline SCHEMBL2827373 | 0.78 | MAOB (1.00) | MAOBMAOAACHEBCHEADRA2B | |
| Rasagiline SCHEMBL74699 | 0.78 | MAOB (1.00) | MAOBMAOAACHEBCHEADRA2B | |
| Rasagiline SCHEMBL12787613 | 0.78 | MAOB (1.00) | MAOBMAOAACHEBCHEADRA2B | |
| Azilect SCHEMBL332967 | 0.78 | MAOB (1.00) | MAOBMAOAACHEBCHEADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097946-A1 | OXAZOLIDINONE COMPOUNDS CONTAINING RING-FUSED BICYCLIC RING, PREPARATION METHOD AND USE THEREOF | 山东轩竹医药科技有限公司 (CN) | 2011-08-18 | — | — | WO | disclosed |
| CN-102153547-A | Oxazolidinone antibiotic containing parallel rings | SHANDONG XUANZHU PHARMACEUTICAL CO LTD OWN | 2011-08-17 | — | — | CN | disclosed |