Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12453239 | 0.93 | IRAK4 (0.38) | IRAK4DYRK1A | |
| SCHEMBL12453235 | 0.92 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL12452792 | 0.89 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL12454025 | 0.89 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL15983128 | 0.86 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL15983132 | 0.86 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL12057876 | 0.85 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL12057722 | 0.82 | IRAK4 (0.38) | IRAK4 | |
| SCHEMBL12454032 | 0.82 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL12454030 | 0.82 | IRAK4 (0.40) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103441-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2011-08-25 | — | — | WO | disclosed |