SCHEMBL1245657

SCHEMBL1245657

CCCOC(=O)C1C(C)CC(C)C1C(=O)OCCC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 2/20 0.50
PTPN1 P18031 2/20 0.50
PPP1CC P36873 2/20 0.50
ALDH1A1 P00352 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HCAR2 Q8TDS4 1/20 0.35
PPARG P37231 3/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27791147 0.93 PPM1B (0.57) PPM1BPTPN1PPP1CCALDH1A1NPSR1
SCHEMBL1196011 0.88 PPM1B (0.59) PPM1BPTPN1PPP1CCALDH1A1NPSR1
SCHEMBL1196016 0.86 PPM1B (0.43) PPM1BPTPN1PPP1CCALDH1A1NPSR1
SCHEMBL1195985 0.85 PPARG (0.49) ALDH1A1NPSR1HCAR2PPARGLMNA
SCHEMBL1195607 0.85 PPARG (0.49) ALDH1A1NPSR1HCAR2PPARGLMNA
SCHEMBL1196040 0.85 PPARG (0.49) ALDH1A1NPSR1HCAR2PPARGLMNA
SCHEMBL1196030 0.85 PPARG (0.49) ALDH1A1NPSR1HCAR2PPARGLMNA
SCHEMBL1244545 0.84 PPM1B (0.51) PPM1BPTPN1PPP1CCALDH1A1NPSR1
SCHEMBL1196516 0.83 PPM1B (0.47) PPM1BPTPN1PPP1CCALDH1A1LMNA
SCHEMBL27709935 0.81 PPM1B (0.66) PPM1BPTPN1PPP1CCALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593175-B2 Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene polymerization method MITSUI CHEMICALS, INC. (JP) 2017-03-14 US disclosed
EP-2264075-B1 SOLID TITANIUM CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, ETHYLENE POLYMERIZATION CATALYST AND ETHYLENE POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2016-05-25 EP disclosed
CN-101983211-B Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene polymerization method MITSUI CHEMICALS INC 2013-05-29 CN disclosed
CN-101842396-B Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2013-03-20 CN disclosed
US-8383541-B2 Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene polymerization method MITSUI CHEMICALS, INC. (JP) 2013-02-26 US disclosed
US-20110269924-A1 SOLID TITANIUM CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, ETHYLENE POLYMERIZATION CATALYST AND ETHYLENE POLYMERIZATION METHOD MITSUI CHEMICALS, INC. 2011-11-03 US disclosed
CN-101983211-A Solid titanium catalyst component for ethylene polymerization, ethylene polymerization catalyst and ethylene polymerization method MITSUI CHEMICALS INC 2011-03-02 CN disclosed
US-20110034648-A1 SOLID TITANIUM CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, ETHYLENE POLYMERIZATION CATALYST AND ETHYLENE POLYMERIZATION METHOD MITSUI CHEMICALS (JP) 2011-02-10 US disclosed
EP-2264075-A1 SOLID TITANIUM CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, ETHYLENE POLYMERIZATION CATALYST AND ETHYLENE POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-12-22 EP disclosed
CN-101842396-A Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2010-09-22 CN disclosed