⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22137667 | 0.85 | KDM4E (0.37) | — | |
| SCHEMBL7290876 | 0.84 | — | — | |
| SCHEMBL6525778 | 0.78 | ANPEP (0.39) | — | |
| SCHEMBL12651871 | 0.74 | — | — | |
| SCHEMBL2263311 | 0.74 | KDM4E (0.41) | — | |
| SCHEMBL3557239 | 0.74 | — | — | |
| SCHEMBL6522093 | 0.74 | ANPEP (0.37) | — | |
| SCHEMBL24400305 | 0.74 | — | — | |
| SCHEMBL6055711 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL6523928 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845350-A | Honokiol derivative and preparation method and application thereof | 广东省禾基生物科技有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110664795-A | Water-soluble composition, preparation method and application thereof | 广东省禾基生物科技有限公司 | 2020-01-10 | — | — | CN | claimed |
| CN-110615742-A | Magnolol derivative and preparation method and application thereof | 广东省禾基生物科技有限公司 | 2019-12-27 | — | — | CN | claimed |
| US-12636290-B2 | BET inhibitors for modulating DUX4 expression in FSHD | SAINT LOUIS UNIVERSITY (US) | 2026-05-26 | — | — | US | disclosed |
| US-20250296931-A1 | NOVEL ISOQUINOLINONE, PYRROLOPYRIDINONE AND THIENOPYRIDINONE SULFONAMIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2025-09-25 | — | — | US | disclosed |
| EP-4558483-A1 | NOVEL ISOQUINOLINONE, PYRROLOPYRIDINONE AND THIENOPYRIDINONE SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-05-28 | — | — | EP | disclosed |
| CN-119546576-A | Novel isoquinolinones pyrrolo-pyridones and thieno pyridone sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-111954848-B | Photosensitive resin composition, cured product, insulating material, resin material for solder resist, and resist member | DIC株式会社 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024017856-A1 | NOVEL ISOQUINOLINONE, PYRROLOPYRIDINONE AND THIENOPYRIDINONE SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-25 | — | — | WO | disclosed |
| CN-110664795-B | Water-soluble composition, preparation method and application thereof | 广东省禾基生物科技有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-109153653-B | Novel compound, photocurable composition, cured product thereof, printing ink, and printed matter using the printing ink | DIC株式会社 | 2022-06-28 | — | — | CN | disclosed |
| CN-102625808-A | Spirocyclic amide derivatives | ASTRAZENECA AB | 2012-08-01 | — | — | CN | disclosed |
| EP-2459572-A2 | SPIROCYCLIC AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |
| US-20110053909-A1 | Compounds - 801 | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2011-03-03 | — | — | US | disclosed |
| WO-2011012896-A2 | COMPOUNDS - 801 | ASTRAZENECA AB (SE) | 2011-02-03 | — | — | WO | disclosed |
| US-20100160321-A1 | IMIDAZOLINONE AND HYDANTOINE DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-06-24 | — | — | US | disclosed |
| US-20100160321-A1 | IMIDAZOLINONE AND HYDANTOINE DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-06-24 | — | — | US | disclosed |
| CN-1620485-A | Polymer derivatives for the treatment of metals | BASF AG (DE) | 2005-05-25 | — | — | CN | disclosed |
| US-4792630-A | REACTING HALOGENOACETALDEHYDE DIALKYLACETAL WITH AMMONIA OR ALKYLAMINE | NIPPON GOSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-12-20 | — | — | US | disclosed |