Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12461614 | 0.89 | RET (0.56) | RET | |
| SCHEMBL12461821 | 0.88 | RET (0.48) | RET | |
| SCHEMBL12461159 | 0.88 | RET (0.48) | RET | |
| SCHEMBL12461830 | 0.87 | ERN1 (0.47) | RETGAK | |
| SCHEMBL12461307 | 0.85 | ERN1 (0.48) | RETGAK | |
| SCHEMBL12461799 | 0.85 | RET (0.48) | RETGAK | |
| SCHEMBL12461825 | 0.84 | RET (0.71) | RET | |
| SCHEMBL13509615 | 0.84 | GAK (0.44) | RETGAK | |
| SCHEMBL1903502 | 0.83 | KDR (0.50) | RETGAK | |
| SCHEMBL12461791 | 0.82 | KDR (0.49) | RETGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207711-A1 | Therapeutic Compounds | MSD K.K. (JP) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207711-A1 | Therapeutic Compounds | WEE2, MARK3, WEE1 | RET 79/4885GAK 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.