Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.44 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | STK10 | O94804 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | YES1 | P07947 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | HCK | P08631 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714900 | 0.88 | KDR (0.54) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1714439 | 0.88 | KDR (0.54) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1715758 | 0.86 | KDR (0.62) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1715521 | 0.81 | KDR (0.55) | KDR | |
| SCHEMBL1715843 | 0.78 | KDR (0.52) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1715778 | 0.77 | KDR (0.53) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1714924 | 0.77 | KDR (0.48) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1714875 | 0.76 | KDR (0.54) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1715211 | 0.76 | KDR (0.47) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL1715115 | 0.76 | KDR (0.47) | KDRABCB1RETMAP3K20RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |