Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463118 | 0.88 | MTOR (0.73) | MTORPIK3CA | |
| SCHEMBL12462998 | 0.82 | MTOR (0.75) | MTORPIK3CA | |
| SCHEMBL13718196 | 0.82 | MTOR (0.85) | MTOR | |
| SCHEMBL12463097 | 0.76 | MTOR (0.49) | MTORKDM4E | |
| SCHEMBL12462999 | 0.76 | ABCC4 (0.48) | MTORPIK3CA | |
| SCHEMBL12463381 | 0.76 | MTOR (0.65) | MTORPIK3CA | |
| SCHEMBL12462985 | 0.76 | MTOR (0.60) | MTORPIK3CA | |
| SCHEMBL12463348 | 0.76 | MTOR (0.50) | MTORPIK3CA | |
| SCHEMBL12462773 | 0.75 | MTOR (0.73) | MTOR | |
| SCHEMBL12463227 | 0.74 | MTOR (0.40) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080568-A2 | NOVEL PYRIMIDINE COMPOUNDS AS MTOR AND P13K INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2011-07-07 | — | — | WO | disclosed |