Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888326 | 0.92 | TSHR (0.46) | TSHRHSD17B10HPGDKDM5AALDH1A1 | |
| SCHEMBL7529082 | 0.82 | MAOB (0.40) | TSHRHSD17B10HPGDKDM5AALDH1A1 | |
| SCHEMBL11637131 | 0.75 | KDM5A (0.42) | TSHRHSD17B10HPGDKDM5AALDH1A1 | |
| SCHEMBL14532525 | 0.73 | KDM5A (0.58) | TSHRHSD17B10HPGDKDM5AERN1 | |
| SCHEMBL7804531 | 0.73 | KDM4E (0.47) | HSD17B10HPGDKDM5AALDH1A1LMNA | |
| SCHEMBL325006 | 0.72 | CA1 (0.50) | TSHRHPGDALDH1A1TDP1LMNA | |
| SCHEMBL30132193 | 0.72 | CA1 (0.50) | TSHRHPGDALDH1A1TDP1LMNA | |
| SCHEMBL1758631 | 0.72 | MEN1 (0.50) | HPGDALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL28620707 | 0.72 | KDM5A (0.55) | TSHRKDM5AALDH1A1CYP3A4TDP1 | |
| SCHEMBL8805026 | 0.72 | TSHR (0.43) | TSHRHSD17B10HPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1722272-B1 | Polymerizable composition and lithographic printing plate precursor | FUJIFILM CORP (JP) | 2011-07-06 | — | — | EP | disclosed |