⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023832 | 1.00 | — | — | |
| SCHEMBL22559995 | 1.00 | — | — | |
| SCHEMBL4406364 | 1.00 | — | — | |
| SCHEMBL100461 | 1.00 | — | — | |
| SCHEMBL7993325 | 1.00 | — | — | |
| SCHEMBL12516356 | 1.00 | — | — | |
| SCHEMBL2528838 | 1.00 | — | — | |
| SCHEMBL24246852 | 0.85 | GBA2 (0.35) | — | |
| SCHEMBL22640981 | 0.85 | GBA2 (0.35) | — | |
| SCHEMBL13969566 | 0.85 | GBA2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230095696-A1 | OLIGOMERIC COMPOUNDS COMPRISING BACKBONE CONSTRAINED MACROCYCLES | IONIS PHARMACEUTICALS, INC. (US) | 2023-03-30 | — | — | US | disclosed |
| US-20170306393-A9 | Method for Detecting Target Nucleic Acid | NGK INSULATORS, LTD. (JP) | 2017-10-26 | — | — | US | disclosed |
| EP-1947092-B1 | Method for producing nucleic acid base having perfluoroalkyl group | TOSOH CORP (JP) | 2015-04-15 | — | — | EP | disclosed |
| WO-2012164484-A1 | ADENOSINE OR DEOXYADENOSINE DERIVATIVES MODIFIED AT POSITION 8 AND A METHOD OF SYNTHESIS THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-12-06 | — | — | WO | disclosed |
| WO-2011081939-A1 | DIRECT SENSING OF MOLECULAR SPECIES BY POLYFLUORS ON A DNA BACKBONE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2010149761-A1 | COMPOSITION FOR TREATMENT OF TUBERCULOSIS | BIOVERSYS GMBH (CH) | 2010-12-29 | — | — | WO | disclosed |
| US-7566775-B2 | N8- and C8-linked purine bases and structurally related heterocycles as universal nucleosides used for oligonucleotides hybridization | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| EP-1301523-B1 | N8 - AND C8 -LINKED PURINE BASES AND STRUCTURALLY RELATED HETEROCYCLES AS UNIVERSAL NUCLEOSIDES USED FOR OLIGONUCLEOTIDE HYBRIDIZATION | ROCHE DIAGNOSTICS GMBH (DE) | 2009-01-14 | — | — | EP | disclosed |
| US-7423133-B2 | Fluorescent glycosides and methods for their use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-09-09 | — | — | US | disclosed |
| EP-1947092-A1 | NUCLEIC ACID BASE HAVING PERFLUOROALKYL GROUP AND METHOD FOR PRODUCING THE SAME | Tosoh Corporation (JP) | 2008-07-23 | — | — | EP | disclosed |