Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12396842 | 0.92 | BRAF (0.69) | BRAF | |
| SCHEMBL23057316 | 0.88 | BRAF (0.78) | BRAFRAF1 | |
| SCHEMBL12465331 | 0.88 | ABL1 (0.55) | BRAF | |
| SCHEMBL12465129 | 0.87 | ABL1 (0.53) | BRAF | |
| SCHEMBL12465275 | 0.87 | BRAF (0.72) | BRAFRAF1 | |
| SCHEMBL12397644 | 0.85 | BRAF (0.69) | BRAF | |
| SCHEMBL23057201 | 0.83 | BRAF (0.77) | BRAFRAF1 | |
| SCHEMBL15133775 | 0.82 | BRAF (1.00) | BRAF | |
| SCHEMBL12464983 | 0.82 | ABL1 (0.50) | BRAF | |
| SCHEMBL2427952 | 0.82 | BRAF (1.00) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889665-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183952-A1 | NEW CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | BRAF 525/4885RAF1 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.