Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466669 | 0.79 | MEN1 (0.65) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12685786 | 0.77 | MEN1 (0.65) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12466320 | 0.76 | MEN1 (0.62) | MEN1KMT2AGRIN2BFAAHUSP2 | |
| SCHEMBL12466583 | 0.75 | MEN1 (0.85) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12685846 | 0.75 | MEN1 (0.85) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12685780 | 0.75 | MEN1 (0.85) | MEN1KMT2AGRIN2BFAAHPOLB | |
| Hydrochloric Acid SCHEMBL12466326 | 0.74 | MEN1 (0.83) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12466627 | 0.74 | MEN1 (0.70) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12685841 | 0.74 | MEN1 (0.70) | MEN1KMT2AGRIN2BFAAHPOLB | |
| SCHEMBL12466655 | 0.74 | MEN1 (0.77) | MEN1KMT2AGRIN2BFAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668157-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | Proximagen Limited (GB) | 2013-12-04 | — | — | EP | disclosed |
| EP-2668182-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC Discovery GmbH (DE) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012101261-A1 | IL17 AND IFN-GAMMA INHIBITION FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION | 4SC DISCOVERY GMH (DE) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | disclosed |