Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.62 |
| ▸ | F2 | P00734 | 5/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.59 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466291 | 0.89 | MEN1 (0.60) | MEN1KMT2ATPSAB1F2PRSS1 | |
| SCHEMBL12466583 | 0.88 | MEN1 (0.85) | MEN1KMT2ANPSR1FAAHSMN1; SMN2 | |
| SCHEMBL12466909 | 0.87 | KMT2A (0.74) | MEN1KMT2ATPSAB1NPSR1FAAH | |
| SCHEMBL12685846 | 0.86 | MEN1 (0.85) | MEN1KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL12685780 | 0.86 | MEN1 (0.85) | MEN1KMT2ATPSAB1NPSR1FAAH | |
| Hydrochloric Acid SCHEMBL12466326 | 0.85 | MEN1 (0.83) | MEN1KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL12466228 | 0.84 | MEN1 (0.77) | MEN1KMT2ANPSR1FAAHSMN1; SMN2 | |
| SCHEMBL12466655 | 0.84 | MEN1 (0.77) | MEN1KMT2ANPSR1FAAHSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL27943775 | 0.81 | KMT2A (0.65) | MEN1KMT2ANPSR1FAAHSMN1; SMN2 | |
| SCHEMBL12468347 | 0.81 | MEN1 (0.71) | MEN1KMT2ANPSR1FAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130324556-A1 | Protease Activated Receptor 2 (PAR2) Antagonists | PROXIMAGEN LTD. (GB) | 2013-12-05 | — | — | US | claimed |
| EP-2668157-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | Proximagen Limited (GB) | 2013-12-04 | — | — | EP | claimed |
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-20130324556-A1 | Protease Activated Receptor 2 (PAR2) Antagonists | PROXIMAGEN LTD. (GB) | 2013-12-05 | — | — | US | disclosed |
| EP-2668157-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | Proximagen Limited (GB) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012101453-A1 | PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISTS | PROXIMAGEN LTD. (GB) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130324556-A1 | Protease Activated Receptor 2 (PAR2) Antagonists | F2RL1, F2R, F2RL3 | MEN1 1376/4885KMT2A 2337/4885TPSAB1 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.