Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 16/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468111 | 0.84 | APP (0.57) | APP | |
| SCHEMBL3190416 | 0.79 | APP (0.74) | APP | |
| SCHEMBL1508061 | 0.77 | APP (1.00) | APPMAOB | |
| SCHEMBL18726332 | 0.77 | SMN1; SMN2 (0.64) | APP | |
| SCHEMBL3188005 | 0.77 | APP (1.00) | APPHDAC6 | |
| SCHEMBL1615482 | 0.76 | APP (0.57) | APP | |
| SCHEMBL12402596 | 0.75 | APP (0.39) | APP | |
| SCHEMBL21566016 | 0.74 | APP (0.67) | APP | |
| SCHEMBL13419361 | 0.74 | APP (0.84) | APPHDAC6 | |
| SCHEMBL12468006 | 0.74 | APP (0.39) | APPHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | MAPT, APP, PSEN1 | APP 2/4885MAOB 537/4885TDO2 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.