Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25402681 | 0.86 | MAPT (0.45) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL3712506 | 0.85 | LPAR1 (0.46) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL25403585 | 0.85 | MAPT (0.42) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL2332531 | 0.85 | LPAR1 (0.52) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL12466213 | 0.85 | LPAR1 (0.49) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL12466003 | 0.84 | MAPT (0.48) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL3714441 | 0.84 | LPAR1 (0.54) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL3712822 | 0.84 | LPAR1 (0.43) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL25236847 | 0.83 | LPAR1 (0.49) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL3706535 | 0.83 | LPAR1 (0.53) | MAPTKDM4ELPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | claimed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |