Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29767699 | 0.89 | TP53 (1.00) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL30694104 | 0.89 | TP53 (1.00) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL2852298 | 0.89 | TP53 (1.00) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL15748043 | 0.82 | TP53 (0.86) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL24224800 | 0.80 | TP53 (0.67) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL10033056 | 0.80 | TP53 (0.67) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL27256804 | 0.80 | TP53 (0.67) | TP53KDM4ETDP1LMNACCR1 | |
| Chloroform SCHEMBL28528314 | 0.80 | TP53 (0.82) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL17301596 | 0.78 | TP53 (0.78) | TP53KDM4ETDP1LMNACCR1 | |
| SCHEMBL10550468 | 0.78 | KDM4E (0.71) | TP53KDM4ETDP1LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039671-A | Organic polymer reinforced natural rubber compound material and preparation method thereof | 山东非金属材料研究所 | 2024-11-29 | — | — | CN | claimed |
| CN-116891599-A | Engineering tire tread rubber composition and preparation method and application thereof | 华勤橡胶工业集团有限公司 | 2023-10-17 | — | — | CN | claimed |
| EP-2922574-B1 | CHEMICALLY CLEAVABLE GROUP | TAGWORKS PHARMACEUTICALS B V (NL) | 2023-05-17 | — | — | EP | claimed |
| US-20210388187-A1 | PNEUMATIC TIRE AND RUBBER COMPOSITION INCLUDING SURFACE-FUNCTIONALIZED CARBON NANOTUBES IN COMBINATION WITH TETRAZINE MODIFIED ELASTOMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2021-12-16 | — | — | US | claimed |
| US-20210388188-A1 | PNEUMATIC TIRE AND RUBBER COMPOSITION INCLUDING TETRAZINE MODIFIED ELASTOMER AND ZINC COMPLEX COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY | 2021-12-16 | — | — | US | claimed |
| EP-3922483-A1 | PNEUMATIC TIRE AND RUBBER COMPOSITION INCLUDING TETRAZINE MODIFIED ELASTOMER AND ZINC COMPLEX COMPOUND | The Goodyear Tire & Rubber Company (US) | 2021-12-15 | — | — | EP | claimed |
| EP-3922484-A1 | PNEUMATIC TIRE AND RUBBER COMPOSITION INCLUDING SURFACE-FUNCTIONALIZED CARBON BLACK AND TETRAZINE MODIFIED ELASTOMER | The Goodyear Tire & Rubber Company (US) | 2021-12-15 | — | — | EP | claimed |
| CN-119039671-A | Organic polymer reinforced natural rubber compound material and preparation method thereof | 山东非金属材料研究所 | 2024-11-29 | — | — | CN | disclosed |
| EP-3594282-B1 | RUBBER COMPOSITION AND TIRE | OTSUKA CHEMICAL CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| EP-4382167-A2 | COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY | Tagworks Pharmaceuticals B.V. (NL) | 2024-06-12 | — | — | EP | disclosed |
| EP-2627358-B1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-03-27 | — | — | EP | disclosed |
| US-20240091371-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2024-03-21 | — | — | US | disclosed |
| EP-3788032-B1 | COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-01-24 | — | — | EP | disclosed |
| WO-2012156919-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012156918-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012156920-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012156920-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012153254-A1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS - CYCLOOCTENE DIENOPHILE AND A DIENE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012153254-A1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS - CYCLOOCTENE DIENOPHILE AND A DIENE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012049624-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240091371-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | JMJD7, KIT, PAICS | TP53 1641/4885KDM4E 1403/4885TDP1 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.