Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468653 | 1.00 | MAPK1 (0.30) | MAPK1MAPK14PTGS1PTGS2 | |
| SCHEMBL15131943 | 1.00 | MAPK1 (0.30) | MAPK1MAPK14PTGS1PTGS2 | |
| SCHEMBL14960420 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL3668341 | 0.77 | — | — | |
| SCHEMBL3668343 | 0.77 | — | — | |
| SCHEMBL17701515 | 0.77 | — | — | |
| SCHEMBL26568342 | 0.77 | — | — | |
| SCHEMBL27407126 | 0.74 | — | — | |
| SCHEMBL30841891 | 0.74 | ATM (0.31) | — | |
| SCHEMBL15131938 | 0.74 | ATM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627358-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | Koninklijke Philips Electronics N.V. (NL) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012049624-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-04-19 | — | — | WO | disclosed |