Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107909 | 0.88 | NAMPT (0.81) | NAMPTCYP2C9 | |
| SCHEMBL164396 | 0.88 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL161138 | 0.83 | NAMPT (0.75) | NAMPTCYP2C9 | |
| SCHEMBL164490 | 0.82 | NAMPT (0.73) | NAMPTCYP2C9 | |
| SCHEMBL16108701 | 0.82 | NAMPT (0.74) | NAMPTCYP2C9 | |
| SCHEMBL16107653 | 0.82 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL12466782 | 0.81 | NAMPT (0.73) | NAMPTCYP2C9 | |
| SCHEMBL12468570 | 0.81 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL16820346 | 0.81 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL16820381 | 0.80 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611804-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Forma TM, LLC. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012031197-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | claimed |