Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468717 | 0.92 | MAPT (0.50) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12468703 | 0.92 | MAPT (0.57) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL15322711 | 0.90 | MAPT (0.55) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12469768 | 0.90 | MAPT (0.51) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12468669 | 0.90 | MAPT (0.60) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12469434 | 0.89 | MAPT (0.54) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12468871 | 0.89 | MAPT (0.53) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL15323530 | 0.89 | HTT (0.55) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12469144 | 0.89 | HTT (0.55) | MAPTTHRBPOLBHTTMEN1 | |
| SCHEMBL12469205 | 0.88 | MAPT (0.58) | MAPTTHRBPOLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627324-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051117-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-04-19 | — | — | WO | disclosed |