Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19133331 | 0.88 | ABL1 (0.46) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1282602 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1707956 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL2739672 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL220474 | 0.82 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1282358 | 0.81 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL2739706 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL13269595 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1682897 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL19159716 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828257-B1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LTD (GB) | 2017-07-26 | — | — | EP | disclosed |
| EP-2828257-A1 | ANTIBACTERIAL COMPOUNDS | Biota Europe Ltd (GB) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013138860-A1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LIMITED (GB) | 2013-09-26 | — | — | WO | disclosed |
| EP-2625178-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | Biota Europe Ltd (GB) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045194-A1 | BENZODIAZEPINONES AS FAK INHIBITORS FOR TREATMENT OF CANCER | ABBOTT LABORATORIES (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |