Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.62 |
| ▸ | GLP1R | P43220 | 3/20 | 0.52 |
| ▸ | GIPR | P48546 | 2/20 | 0.52 |
| ▸ | GCG | P01275 | 6/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11900083 | 0.89 | GCGR (0.79) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL12470608 | 0.86 | GCGR (0.80) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL12470490 | 0.86 | GCGR (0.80) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL11901120 | 0.86 | GCGR (0.58) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL12470596 | 0.85 | GCGR (0.81) | GCGRGLP1RGIPRGCG | |
| SCHEMBL12470878 | 0.85 | GCGR (0.81) | GCGRGLP1RGIPRGCG | |
| SCHEMBL11962689 | 0.83 | GCGR (0.58) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL12470707 | 0.82 | GCGR (0.79) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL11900284 | 0.81 | GCGR (0.69) | GCGRGLP1RGIPRGCGCHRM5 | |
| SCHEMBL17108957 | 0.80 | GCGR (0.59) | GCGRGLP1RGIPRGCGCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673260-A1 | GLUCAGON RECEPTOR MODULATOR | Pfizer Inc (US) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107850-A1 | GLUCAGON RECEPTOR MODULATOR | PFIZER INC. (US) | 2012-08-16 | — | — | WO | disclosed |