SCHEMBL12470864

SCHEMBL12470864

CCOC(=O)CC(NCCCCC(CCCNC(CC)(C(=O)O)C(CC)C(=O)O)CNC(CC(=O)OCC)C(=O)OCC)C(=O)OCC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12470859 0.82 KMT2A (0.40) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL16016332 0.74 KMT2A (0.45) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL13791979 0.70 KMT2A (0.47) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL31121509 0.70 KMT2A (0.47) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL15862759 0.70 KMT2A (0.41) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL13093481 0.70 KMT2A (0.41) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL16005568 0.67
SCHEMBL12470925 0.67 KMT2A (0.44) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL16239915 0.67 KMT2A (0.42) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL27641985 0.67 KMT2A (0.44) CYP1A2CYP2C9CYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673311-B1 TISSUE ADHESIVE BASED ON TRIFUNCTIONAL ASPARTATES BAYER MATERIALSCIENCE AG (DE) 2014-09-10 EP disclosed
EP-2673311-A1 TISSUE ADHESIVE BASED ON TRIFUNCTIONAL ASPARTATES Bayer Materialscience AG (DE) 2013-12-18 EP disclosed
WO-2012107386-A1 TISSUE ADHESIVE BASED ON TRIFUNCTIONAL ASPARTATES BAYER MATERIALSCIENCE AG (DE) 2012-08-16 WO disclosed