Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899959 | 0.91 | CCNT1 (0.36) | BCHECHRM2KMT2APRCPDYRK1A | |
| SCHEMBL900555 | 0.90 | CHRM2 (0.33) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL901286 | 0.90 | MAPK1 (0.34) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| SCHEMBL900609 | 0.88 | CHRM2 (0.39) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| Oxalic Acid SCHEMBL900546 | 0.87 | BCHE (0.38) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| SCHEMBL2720629 | 0.86 | CHRM2 (0.36) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| SCHEMBL900392 | 0.86 | PRCP (0.36) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| SCHEMBL17491677 | 0.85 | CHRM2 (0.36) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| SCHEMBL900545 | 0.84 | BCHE (0.35) | BCHEHTR1ACHRM2ADRA2ACYP2D6 | |
| SCHEMBL900530 | 0.84 | TSHR (0.38) | HTR1ACHRM2ADRA2ACYP2D6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621916-B1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2016-02-10 | — | — | EP | disclosed |
| EP-2621916-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041860-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2012-04-05 | — | — | WO | disclosed |