Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | OPA1 | O60313 | 1/20 | 0.36 |
| ▸ | EIF5B | O60841 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12572709 | 0.88 | HTR2C (0.39) | HTR2AHTR2CALOX15CASP1MTNR1A | |
| SCHEMBL2019928 | 0.88 | HTR2A (0.41) | HTR2AHTR2CDRD4ALOX15CASP1 | |
| Hydrochloric Acid SCHEMBL2019691 | 0.87 | HTR2C (0.38) | HTR2AHTR2CALOX15CASP1MTNR1A | |
| SCHEMBL2016940 | 0.84 | HTR2C (0.38) | HTR2AHTR2CALOX15CASP1MTNR1A | |
| SCHEMBL2018084 | 0.83 | HTR2C (0.37) | HTR2AHTR2CALOX15CASP1MTNR1A | |
| SCHEMBL2017661 | 0.81 | NPC1 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL2021027 | 0.73 | HTR2A (0.39) | HTR2AHTR2CALOX15CASP1MTNR1A | |
| SCHEMBL2018600 | 0.67 | HTR2A (0.46) | HTR2AHTR2CMTNR1AMTNR1BOPA1 | |
| SCHEMBL12475277 | 0.66 | EGFR (0.46) | HTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL10100276 | 0.66 | HTR2A (0.59) | HTR2AHTR2CMTNR1AMTNR1BOPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082266-A2 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | ARQULE, INC. (US) | 2011-07-07 | — | — | WO | disclosed |