Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475505 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL4473861 | 0.83 | KDM4E (0.54) | MAPTNPC1KDM4ETRPM8GAA | |
| SCHEMBL10237187 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL8339292 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL5255659 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL12475892 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL12475538 | 0.78 | PTPN11 (0.60) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL12475559 | 0.78 | MAPT (0.48) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL12475391 | 0.77 | PTPN11 (0.56) | SMN1; SMN2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL2580488 | 0.77 | PTPN11 (0.53) | SMN1; SMN2MAPTRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012109573-A1 | SUBSTITUTED THIAZOLES FOR USE AS ANTIVIRAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2012-08-16 | — | — | WO | disclosed |