Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.38 |
| ▸ | ACACA | Q13085 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17050441 | 0.88 | ACACB (0.47) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL12476184 | 0.84 | ACACB (0.49) | ACACBACACACYP2C9CYP2C19NPC1 | |
| SCHEMBL12476320 | 0.81 | ACACB (0.56) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL17050439 | 0.81 | ACACB (0.45) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL17050438 | 0.81 | ACACB (0.43) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL17050442 | 0.79 | ACACB (0.43) | ACACBACACACYP2C9CYP2C19NPC1 | |
| SCHEMBL17050444 | 0.78 | ACACB (0.44) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL983839 | 0.75 | TDP1 (0.47) | NPC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17050448 | 0.75 | ACACB (0.37) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL17050450 | 0.75 | HPGD (0.38) | ACACBACACACYP2C9CYP2C19PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |