Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3532203 | 0.83 | DPP4 (0.35) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL17137865 | 0.81 | DPP4 (0.35) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL3539136 | 0.80 | DPP4 (0.33) | DPP4DPP7ALDH1A1 | |
| SCHEMBL17137872 | 0.80 | DPP4 (0.33) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL12476768 | 0.80 | DPP4 (0.45) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL17137867 | 0.79 | DPP4 (0.31) | DPP4DPP7DPP9CYP2D6KCNH2 | |
| SCHEMBL17137855 | 0.79 | DPP4 (0.33) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL17137856 | 0.79 | DPP4 (0.33) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL3533168 | 0.79 | DPP4 (0.43) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL12476482 | 0.78 | CYP2D6 (0.33) | DPP4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012089123-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2012-07-05 | — | — | WO | disclosed |