Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 14/20 | 0.56 |
| ▸ | FLT4 | P35916 | 9/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12478142 | 0.89 | PTK2 (0.49) | PTK2FLT4KDR | |
| SCHEMBL14576969 | 0.87 | PTK2 (0.48) | PTK2FLT4KDR | |
| SCHEMBL14576563 | 0.81 | PTK2 (0.53) | PTK2FLT4KDR | |
| SCHEMBL12478967 | 0.80 | PTK2 (0.50) | PTK2FLT4KDR | |
| SCHEMBL15514223 | 0.77 | PTK2 (0.54) | PTK2FLT4KDR | |
| SCHEMBL15512969 | 0.76 | PTK2 (0.51) | PTK2FLT4KDR | |
| SCHEMBL14576493 | 0.75 | PTK2 (0.49) | PTK2FLT4KDR | |
| SCHEMBL15524884 | 0.73 | PTK2 (0.43) | PTK2FLT4KDR | |
| SCHEMBL15514817 | 0.73 | PTK2 (0.48) | PTK2FLT4KDR | |
| SCHEMBL12478260 | 0.73 | PTK2 (0.54) | PTK2FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675793-A1 | FAK INHIBITORS | Cancer Therapeutics Crc Pty Limited (AU) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110773-A1 | FAK INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2012-08-23 | — | — | WO | disclosed |