Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483305 | 0.81 | KMT2A (0.49) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL10849722 | 0.80 | KMT2A (0.51) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL12485791 | 0.78 | KMT2A (0.46) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL12485725 | 0.75 | KMT2A (0.44) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL12484176 | 0.75 | KMT2A (0.44) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL12483838 | 0.74 | KMT2A (0.42) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL17386207 | 0.74 | KMT2A (0.41) | KMT2AKDM4EHTTMEN1 | |
| SCHEMBL1603021 | 0.73 | KMT2A (0.67) | KMT2AKDM4ECRHR1HTTMEN1 | |
| SCHEMBL12485046 | 0.73 | HSP90AB1 (0.31) | — | |
| SCHEMBL12484926 | 0.73 | KMT2A (0.41) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012115479-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2012-08-30 | — | — | WO | disclosed |