Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248466 | 1.00 | CHRM2 (0.32) | CHRM2CHRM1KDM4EALDH1A1 | |
| SCHEMBL994410 | 0.84 | NR1H2 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL994409 | 0.84 | NR1H2 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL1251171 | 0.75 | CHRM2 (0.33) | CHRM2CHRM1 | |
| SCHEMBL1251172 | 0.75 | CHRM2 (0.33) | CHRM2CHRM1 | |
| SCHEMBL5186361 | 0.65 | CHRM2 (0.31) | CHRM2CHRM1 | |
| SCHEMBL5260871 | 0.65 | CHRM2 (0.31) | CHRM2CHRM1 | |
| SCHEMBL1249643 | 0.65 | GAA (0.30) | — | |
| SCHEMBL5257624 | 0.65 | CHRM2 (0.33) | CHRM2CHRM1 | |
| SCHEMBL5257617 | 0.65 | CHRM2 (0.33) | CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279737-B1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2012-10-31 | — | — | EP | disclosed |
| EP-2279737-A1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1480644-B1 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | NOVEXEL (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1307457-B1 | AZABICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE AS MEDICINES, IN PARTICULAR AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-04-07 | — | — | EP | disclosed |