Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.46 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.46 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.46 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844837 | 0.96 | POLM (0.50) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL14845171 | 0.95 | POLM (0.52) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL12484603 | 0.95 | POLM (0.52) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL14844980 | 0.95 | POLM (0.52) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL12485236 | 0.85 | KMT2A (0.45) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL14844839 | 0.81 | POLM (0.49) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL14844977 | 0.81 | PTPN1 (0.46) | KMT2AKDM4EMEN1HTR2APOLB | |
| SCHEMBL12484604 | 0.81 | POLM (0.51) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL14844982 | 0.81 | POLM (0.51) | KMT2AKDM4EMEN1RECQLPOLM | |
| SCHEMBL14845172 | 0.81 | POLM (0.51) | KMT2AKDM4EMEN1RECQLPOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678341-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM Pharma Co., Ltd. (JP) | 2014-01-01 | — | — | EP | claimed |
| WO-2012115286-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-08-30 | — | — | WO | claimed |
| EP-2763995-A1 | CBP/CATENIN ANTAGONISTS FOR ENHANCING ASYMMETRIC DIVISION OF SOMATIC STEM CELLS | University of Southern California (US) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013052162-A1 | CBP/CATENIN ANTAGONISTS FOR ENHANCING ASYMMETRIC DIVISION OF SOMATIC STEM CELLS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-04-11 | — | — | WO | disclosed |