Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483890 | 0.88 | CNR2 (0.48) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL15742957 | 0.86 | CNR2 (0.61) | CNR1CNR2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2053427 | 0.82 | CNR2 (0.55) | CNR1CNR2ALDH1A1TSHRKDM4C | |
| SCHEMBL24437338 | 0.80 | KCNH2 (0.50) | CNR1CNR2KDM4C | |
| SCHEMBL12483796 | 0.80 | NR4A2 (0.45) | CNR1CNR2KDM4EALDH1A1NR4A2 | |
| SCHEMBL11404246 | 0.78 | KDM4E (0.51) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL2429622 | 0.78 | NR4A2 (0.69) | KDM4EALDH1A1NR4A2LMNAKMT2A | |
| SCHEMBL30373303 | 0.78 | NR4A2 (0.69) | KDM4EALDH1A1NR4A2LMNAKMT2A | |
| SCHEMBL13967349 | 0.77 | KDM4E (0.51) | CNR1CNR2KDM4EALDH1A1TSHR | |
| SCHEMBL26661966 | 0.74 | CYP19A1 (0.38) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012114252-A1 | NOVEL INDOLE AND PYRROLOPYRIDINE AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-08-30 | — | — | WO | disclosed |