Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 19/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.81 |
| ▸ | CASP1 | P29466 | 1/20 | 0.81 |
| ▸ | CASP7 | P55210 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487777 | 0.85 | MCL1 (1.00) | MCL1 | |
| SCHEMBL12488641 | 0.85 | MCL1 (1.00) | MCL1 | |
| SCHEMBL12488436 | 0.85 | MCL1 (1.00) | MCL1 | |
| SCHEMBL12487582 | 0.83 | MCL1 (1.00) | MCL1 | |
| SCHEMBL12488854 | 0.80 | MCL1 (1.00) | MCL1 | |
| SCHEMBL12488669 | 0.80 | MCL1 (1.00) | MCL1 | |
| SCHEMBL12488491 | 0.80 | MCL1 (0.70) | MCL1LMNAMAPT | |
| SCHEMBL12488427 | 0.80 | MCL1 (1.00) | MCL1MAPT | |
| SCHEMBL12488536 | 0.79 | MCL1 (1.00) | MCL1MAPT | |
| SCHEMBL12488800 | 0.79 | MCL1 (1.00) | MCL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684167-B1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS INC (US) | 2020-09-09 | — | — | EP | claimed |
| US-9345700-B2 | Compositions and methods useful for treating diseases | EUTROPICS PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | claimed |
| US-9051305-B2 | Compositions and methods useful for treating diseases | EUTROPICS PHARMACEUTICALS, INC. (US) | 2015-06-09 | — | — | US | claimed |
| US-20140221387-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | claimed |
| EP-2684167-B1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS INC (US) | 2020-09-09 | — | — | EP | disclosed |
| US-9345700-B2 | Compositions and methods useful for treating diseases | EUTROPICS PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150352097-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS, INC. | 2015-12-10 | — | — | US | disclosed |
| US-9051305-B2 | Compositions and methods useful for treating diseases | EUTROPICS PHARMACEUTICALS, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20140221387-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| EP-2684167-A2 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | Eutropics Pharmaceuticals, Inc. (US) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012122370-A2 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221387-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | BCL3, MCL1, BCL6 | MCL1 2/4885KDM4E 486/4885ALDH1A1 3497/4885 |
| US-20150352097-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | BCL3, MCL1, BCL6 | MCL1 2/4885KDM4E 486/4885ALDH1A1 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.