Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487180 | 0.96 | ATM (0.41) | ATMPRKDCADKCHEK2CHEK1 | |
| SCHEMBL12489939 | 0.90 | ATM (0.38) | ATMPRKDCADKHPGDS | |
| SCHEMBL12488638 | 0.88 | ATM (0.40) | ATMPRKDCADKHPGDSCHEK2 | |
| SCHEMBL12489907 | 0.86 | PRKDC (0.41) | ATMPRKDCADK | |
| SCHEMBL12489912 | 0.86 | PRKDC (0.43) | ATMPRKDCADK | |
| SCHEMBL12489648 | 0.85 | PRKDC (0.43) | ATMPRKDCADK | |
| SCHEMBL12490592 | 0.84 | NPC1 (0.40) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL12487694 | 0.83 | PRKDC (0.38) | ATMPRKDCADK | |
| SCHEMBL12487194 | 0.83 | ATM (0.42) | ATMPRKDCADKHPGDSCHEK2 | |
| SCHEMBL18960930 | 0.83 | PRKDC (0.37) | ATMPRKDCADKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011081451-A2 | TRI-PHENYL COMPOUNDS AND ORGANIC ELECTRO-LUMINESCENT DEVICE USING SAME | 주식회사 두산 (KR) | 2011-07-07 | — | — | WO | disclosed |