Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 4/20 | 0.49 |
| ▸ | MAP3K14 | Q99558 | 15/20 | 0.46 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12490306 | 1.00 | TTBK1 (0.51) | TTBK1PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11971043 | 0.87 | MAP3K14 (0.48) | PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11970276 | 0.87 | MAP3K14 (0.49) | PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11970478 | 0.87 | MAP3K14 (0.49) | PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11970822 | 0.87 | MAP3K14 (0.49) | PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11970583 | 0.86 | PAK4 (0.55) | PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11970877 | 0.85 | PAK4 (0.53) | TTBK1PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11971053 | 0.84 | PAK4 (0.47) | TTBK1PAK4MAP3K14PIKFYVE | |
| SCHEMBL11970453 | 0.83 | PAK4 (0.52) | PAK4MAP3K14PIKFYVEPRKD1 | |
| SCHEMBL11970468 | 0.83 | PAK4 (0.52) | PAK4MAP3K14PIKFYVEPRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2686314-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | F.HOFFMANN-LA ROCHE AG (CH) | 2014-01-22 | — | — | EP | claimed |
| WO-2012123522-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-20 | — | — | WO | claimed |