Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.67 |
| ▸ | AKT2 | P31751 | 12/20 | 0.65 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189239 | 0.95 | AKT1 (0.72) | AKT1AKT2AKT3 | |
| SCHEMBL2192537 | 0.94 | AKT1 (0.66) | AKT1AKT2AKT3 | |
| SCHEMBL2190968 | 0.94 | AKT1 (0.65) | AKT1AKT2AKT3 | |
| SCHEMBL2191349 | 0.91 | AKT1 (0.62) | AKT1AKT2AKT3 | |
| SCHEMBL2173590 | 0.91 | AKT1 (0.62) | AKT1AKT2AKT3 | |
| SCHEMBL2191050 | 0.91 | AKT1 (0.65) | AKT1AKT2AKT3 | |
| SCHEMBL2176672 | 0.90 | AKT1 (0.68) | AKT1AKT2AKT3 | |
| SCHEMBL2177003 | 0.90 | AKT1 (0.67) | AKT1AKT2AKT3 | |
| SCHEMBL2189218 | 0.90 | AKT1 (0.67) | AKT1AKT2AKT3 | |
| SCHEMBL2173566 | 0.89 | AKT1 (0.63) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082270-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE. INC. (US) | 2011-07-07 | — | — | WO | disclosed |