Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249484 | 1.00 | ACE (0.37) | ACEPOLBGAA | |
| SCHEMBL1249483 | 1.00 | ACE (0.37) | ACEPOLBGAA | |
| SCHEMBL1249485 | 1.00 | ACE (0.37) | ACEPOLBGAA | |
| SCHEMBL1249827 | 0.86 | ACE (0.39) | ACEPOLBGAA | |
| SCHEMBL1249824 | 0.86 | ACE (0.39) | ACEPOLBGAA | |
| SCHEMBL1249829 | 0.86 | ACE (0.39) | ACEPOLBGAA | |
| SCHEMBL1249826 | 0.86 | ACE (0.39) | ACEPOLBGAA | |
| SCHEMBL22522781 | 0.80 | POLB (0.34) | ACEPOLBGAA | |
| SCHEMBL18615327 | 0.80 | POLB (0.34) | ACEPOLBGAA | |
| SCHEMBL1250692 | 0.80 | ACE (0.41) | ACEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279737-B1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2012-10-31 | — | — | EP | disclosed |
| EP-2279737-A1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1480644-B1 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | NOVEXEL (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1307457-B1 | AZABICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE AS MEDICINES, IN PARTICULAR AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-04-07 | — | — | EP | disclosed |