Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 12/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12688187 | 0.86 | CTSC (0.50) | SMN1; SMN2TSHRCTSCCTSKCTSL | |
| SCHEMBL12494542 | 0.86 | CTSC (0.50) | SMN1; SMN2TSHRCTSCCTSKCTSL | |
| SCHEMBL12494546 | 0.86 | CTSC (0.50) | SMN1; SMN2TSHRCTSCCTSKCTSL | |
| SCHEMBL2890331 | 0.85 | CTSC (0.51) | SMN1; SMN2TSHRCTSCCTSKCTSL | |
| SCHEMBL12494582 | 0.82 | CTSC (0.46) | CTSCCTSKCYP1A2CYP3A4CTSH | |
| SCHEMBL290127 | 0.79 | CTSC (0.54) | SMN1; SMN2CTSCCTSKCTSLCTSB | |
| SCHEMBL289040 | 0.78 | CTSC (0.57) | SMN1; SMN2CTSCCTSKCTSLCTSB | |
| SCHEMBL12687951 | 0.78 | CTSC (0.63) | SMN1; SMN2CTSCCTSKCTSLCTSB | |
| SCHEMBL12494572 | 0.78 | CTSC (0.51) | SMN1; SMN2TSHRCTSCCTSKALDH1A1 | |
| SCHEMBL289757 | 0.76 | CTSC (0.66) | SMN1; SMN2CTSCCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012119941-A1 | PEPTIDYL NITRILCOMPOUNDS AS PEPTIDASE INHIBITORS | PROZYMEX A/S (DK) | 2012-09-13 | — | — | WO | disclosed |