Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562510 | 0.83 | PIK3CA (0.60) | PIK3CAMTOR | |
| SCHEMBL12498352 | 0.82 | PIK3CA (0.62) | PIK3CAMTOR | |
| SCHEMBL6894356 | 0.78 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL19241997 | 0.77 | PIK3CA (0.52) | PIK3CAMTOR | |
| SCHEMBL12499795 | 0.76 | PIK3CA (0.51) | PIK3CAMTOR | |
| SCHEMBL12499760 | 0.74 | PIK3CA (0.70) | PIK3CAMTOR | |
| SCHEMBL6897199 | 0.72 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL19241868 | 0.72 | PIK3CA (0.76) | PIK3CAMTOR | |
| SCHEMBL12499914 | 0.71 | PIK3CA (0.70) | PIK3CAMTOR | |
| SCHEMBL19242087 | 0.70 | PIK3CA (0.74) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668179-B1 | NEW 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2668179-B1 | NEW 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2668179-A1 | NEW 5-ALKYNYL-PYRIDINES | Boehringer Ingelheim International GmbH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-8598157-B2 | 5-alkynyl-pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| US-20130023519-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-24 | — | — | US | disclosed |
| US-20130023519-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-24 | — | — | US | disclosed |
| EP-2546249-A1 | 5-Alkynyl-pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012101186-A1 | NEW 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023519-A1 | 5-ALKYNYL-PYRIDINES | PIK3CA, PTEN, PIK3CD | PIK3CA 1/4885MTOR 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.