Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17088164 | 0.80 | TSHR (0.42) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL22115423 | 0.79 | — | — | |
| SCHEMBL2050476 | 0.76 | TSHR (0.38) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL5574596 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 | |
| SCHEMBL5843476 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 | |
| SCHEMBL23658246 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 | |
| SCHEMBL14910494 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 | |
| SCHEMBL6057151 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 | |
| SCHEMBL6474521 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 | |
| SCHEMBL2430911 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1LSSDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658877-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | Bridgestone Corporation (JP) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012092626-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |